Retinal Protection from Acute Glaucoma-Induced Ischemia-Reperfusion Injury through Pharmacologic Induction of Heme Oxygenase-1 | Zendy

MingHui Sun | Zendy; JongHwei S. Pang | Zendy; ShowLi Chen | Zendy; Wen-Hua Han | Zendy; TsungChuan Ho | Zendy; KuanJen Chen | Zendy; Ling-Yuh Kao | Zendy; KenKuo Lin | Zendy; YeouPing Tsao | Zendy

Open Access

Retinal Protection from Acute Glaucoma-Induced Ischemia-Reperfusion Injury through Pharmacologic Induction of Heme Oxygenase-1

Author(s) -

MingHui Sun,

JongHwei S. Pang,

ShowLi Chen,

Wen-Hua Han,

TsungChuan Ho,

KuanJen Chen,

Ling-Yuh Kao,

KenKuo Lin,

YeouPing Tsao

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-4086

Subject(s) - copp , heme oxygenase , retina , retinal , nitric oxide synthase , outer nuclear layer , reperfusion injury , pharmacology , ischemia , inner nuclear layer , chemistry , apoptosis , nitric oxide , microbiology and biotechnology , medicine , biology , endocrinology , heme , biochemistry , neuroscience , enzyme

To investigate the protective effects of cobalt protoporphyrin (CoPP), a potent heme oxygenase (HO)-1 inducer, in a rat model of ischemia-reperfusion injury and to document the possible antiapoptotic and anti-inflammatory mechanisms underlying the protection.

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