Open AccessFunction of MYO7A in the Human RPE and the Validity of Shaker1 Mice as a Model for Usher Syndrome 1B
Author(s) -
Daniel Gibbs,
Tanja Diemer,
Kornnika Khanobdee,
Jane Hu,
Dean Bok,
David S. Williams
Publication year - 2010
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.09-4032
Subject(s) - motility , microbiology and biotechnology , melanosome , biology , phagocytosis , immunofluorescence , phenotype , immunology , antibody , genetics , melanin , gene
To investigate the function of MYO7A in human RPE cells and to test the validity of using shaker1 RPE in preclinical studies on therapies for Usher syndrome 1B by comparing human and mouse cells.
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