Decreased Gray Matter Concentration in the Lateral Geniculate Nuclei in Human Amblyopes | Zendy

Gareth R. Barnes | Zendy; Xingfeng Li | Zendy; Benjamin Thompson | Zendy; Krish D. Singh | Zendy; Serge O. Dumoulin | Zendy; Robert F. Hess | Zendy

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Decreased Gray Matter Concentration in the Lateral Geniculate Nuclei in Human Amblyopes

Author(s) -

Gareth R. Barnes,

Xingfeng Li,

Benjamin Thompson,

Krish D. Singh,

Serge O. Dumoulin,

Robert F. Hess

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-3931

Subject(s) - lateral geniculate nucleus , geniculate , visual cortex , neuroscience , cortex (anatomy) , functional magnetic resonance imaging , thalamus , geniculate body , striate cortex , human brain , psychology , anatomy , biology , nucleus

In a group of humans with strabismic amblyopia, the relationship was examined between the structure and function of different brain regions. Three question were addressed: (1) Is the lateral geniculate nucleus (LGN) in humans with amblyopia structurally as well as functionally abnormal? (2) Do structural anomalies in the visual cortex correlate with the previously reported cortical functional losses? (3) Is there a link between the functional anomalies in the visual cortex and any structural anomalies in the geniculate?

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