Usingneurogeninto Reprogram Chick RPE to Produce Photoreceptor-like Neurons | Zendy

Xiumei Li | Zendy; Wenxin Ma | Zendy; Yehong Zhuo | Zendy; RunTao Yan | Zendy; Shuzhen Wang | Zendy

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Usingneurogeninto Reprogram Chick RPE to Produce Photoreceptor-like Neurons

Author(s) -

Xiumei Li,

Wenxin Ma,

Yehong Zhuo,

RunTao Yan,

Shuzhen Wang

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-3822

Subject(s) - biology , reprogramming , microbiology and biotechnology , retinal pigment epithelium , retinal , visual phototransduction , transducin , retina , opsin , embryo , photoreceptor cell , embryonic stem cell , recoverin , genetics , cell , signal transduction , gene , rhodopsin , neuroscience , biochemistry , g protein

One potential therapy for vision loss from photoreceptor degeneration is cell replacement, but this approach presents a need for photoreceptor cells. This study explores whether the retinal pigment epithelium (RPE) could be a convenient source of developing photoreceptors.

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