Influence of Dosage Form on the Intravitreal Pharmacokinetics of Diclofenac
Author(s) -
Chandrasekar Durairaj,
Stephen J. Kim,
Henry F. Edelhauser,
Jaymin C. Shah,
Uday B. Kompella
Publication year - 2009
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.09-3565
Subject(s) - pharmacokinetics , diclofenac sodium , diclofenac , choroid , chromatography , chemistry , pharmacology , dosage form , vitreous chamber , ophthalmology , retina , medicine , biochemistry , eye disease , biology , neuroscience , refractive error
To prepare a suspension form of diclofenac and compare the influence of the injected form (suspension versus solution) on the intravitreal pharmacokinetics of diclofenac in Dutch belted pigmented rabbits.
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