Regulation of Interphotoreceptor Retinoid-Binding Protein (IRBP)-Specific Th1 and Th17 Cells in Anterior Chamber-Associated Immune Deviation (ACAID) | Zendy

Yan Cui | Zendy; Hui Shao | Zendy; Deming Sun | Zendy; Henry J. Kaplan | Zendy

Open Access

Regulation of Interphotoreceptor Retinoid-Binding Protein (IRBP)-Specific Th1 and Th17 Cells in Anterior Chamber-Associated Immune Deviation (ACAID)

Author(s) -

Yan Cui,

Hui Shao,

Deming Sun,

Henry J. Kaplan

Publication year - 2009

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-3389

Subject(s) - microbiology and biotechnology , population , immunology , immune system , t cell , chemistry , medicine , biology , environmental health

Intracameral (anterior chamber) injection of antigen inhibits the development of delayed-type hypersensitivity, a phenomenon known as anterior chamber-associated immune deviation (ACAID). The authors investigated the effect of intracameral injection of interphotoreceptor retinoid-binding protein (IRPB) peptides on the development of IFN-gamma(+) and IL-17(+) pathogenic T cells.

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