Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema
Author(s) -
Matthew D. Davis,
Matthew J. Sheetz,
Lloyd Paul Aiello,
Roy C. Milton,
Ronald P. Danis,
Xin Zhi,
Aniz Girach,
María Cristina Hernández Jiménez,
Louis Vignati
Publication year - 2009
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.08-2473
Subject(s) - medicine , diabetic retinopathy , ophthalmology , placebo , fundus (uterus) , visual acuity , diabetes mellitus , diabetic macular edema , macular edema , endocrinology , alternative medicine , pathology
To compare relationships between severity and duration of diabetic macular edema (DME) and visual acuity (VA) observed in the PKC-DRS2 with those from the Early Treatment Diabetic Retinopathy Study (ETDRS) and to assess the effect of the orally administered PKC beta inhibitor ruboxistaurin (RBX) on these parameters.
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