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In Vivo Protection against Retinal Neurodegeneration by Sigma Receptor 1 Ligand (+)-Pentazocine
Author(s) -
Sylvia B. Smith,
Jennifer Duplantier,
Ying Dun,
Barbara A. Mysona,
Penny Roon,
Pamela M. Martin,
Vadivel Ganapathy
Publication year - 2008
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.08-1824
Subject(s) - nitrotyrosine , retina , retinal , ganglion cell layer , neurodegeneration , neuroprotection , inner plexiform layer , chemistry , endocrinology , retinal ganglion cell , biology , medicine , microbiology and biotechnology , nitric oxide synthase , pharmacology , nitric oxide , biochemistry , neuroscience , disease
To evaluate the neuroprotective properties of the sigma receptor 1 (sigmaR1) ligand, (+)-pentazocine in an in vivo model of retinal neurodegeneration.

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