Open AccessPD-L1: PD-1 Interaction Contributes to the Functional Suppression of T-Cell Responses to Human Uveal Melanoma Cells In Vitro
Author(s) -
Wanhua Yang,
Peter W. Chen,
Haochuan Li,
Hassan Alizadeh,
Jérry Y. Niederkorn
Publication year - 2008
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.07-1606
Subject(s) - melanoma , jurkat cells , cancer research , cell culture , t cell , downregulation and upregulation , uvea , immunohistochemistry , immune system , tumor microenvironment , cell , chemistry , in vitro , immunology , medicine , biology , biochemistry , gene , genetics
To assess the expression of PD-L1 on human uveal melanomas and its potential to suppress T-cell function.
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