Increased Choroidal Neovascularization following Laser Induction in Mice Lacking Lysyl Oxidase-like 1 | Zendy

Hyeong Gon Yu | Zendy; Xiaoqing Liu | Zendy; Szilárd Kiss | Zendy; E. Connolly | Zendy; Evangelos S. Gragoudas | Zendy; Norman Michaud | Zendy; Oleg V. Bulgakov | Zendy; Michael Adamian | Zendy; Margaret M. DeAngelis | Zendy; Joan W. Miller | Zendy; Tiansen Li | Zendy; Ivana K. Kim | Zendy

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Increased Choroidal Neovascularization following Laser Induction in Mice Lacking Lysyl Oxidase-like 1

Author(s) -

Hyeong Gon Yu,

Xiaoqing Liu,

Szilárd Kiss,

E. Connolly,

Evangelos S. Gragoudas,

Norman Michaud,

Oleg V. Bulgakov,

Michael Adamian,

Margaret M. DeAngelis,

Joan W. Miller,

Tiansen Li,

Ivana K. Kim

Publication year - 2008

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.07-1508

Subject(s) - elastin , elastic fiber , lysyl oxidase , choroidal neovascularization , angiogenesis , matrix metalloproteinase , chemistry , elastase , vascular endothelial growth factor , neovascularization , pathology , microbiology and biotechnology , biology , extracellular matrix , retinal , medicine , cancer research , biochemistry , enzyme , vegf receptors

Age-related degradation of the elastic lamina in Bruch's membrane may have a permissive effect on the growth of choroidal neovascularization (CNV). This study investigated the influence of defective elastic fiber maintenance in the development of laser-induced CNV.

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