Open AccessContribution of TRPV1 to Microglia-Derived IL-6 and NFκB Translocation with Elevated Hydrostatic Pressure
Author(s) -
Rebecca M. Sappington,
David J. Calkins
Publication year - 2008
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.07-1355
Subject(s) - hydrostatic pressure , chemistry , microglia , trpv1 , capsazepine , endocrinology , medicine , transient receptor potential channel , receptor , biology , biochemistry , inflammation , physics , thermodynamics
The authors investigated the contributions of the transient receptor potential vanilloid-1 receptor (TRPV1) and Ca(2+) to microglial IL-6 and nuclear factor kappa B (NFkappaB) translocation with elevated hydrostatic pressure.
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