Evidence of Widespread Retinal Dysfunction in Patients with Stargardt Disease and Morphologically Unaffected Carrier Relatives
Author(s) -
Susana Maia-Lopes,
Eduardo Silva,
Maria Fa ́tima Silva,
Aldina Reis,
Pedro Faria,
Miguel CasteloBranco
Publication year - 2008
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.07-1051
Subject(s) - electroretinography , abca4 , parvocellular cell , stargardt disease , achromatic lens , ophthalmology , erg , medicine , biology , choroideremia , retinal , genetics , optometry , optics , phenotype , gene , physics , central nervous system
To characterize contrast sensitivity (CS) across the visual field for two achromatic spatial-temporal frequencies in 21 families with Stargardt disease (STGD) and to correlate psychophysical impairment with patterns of change in multifocal electroretinography (mfERG).
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