Antiadhesive Character of Mucin O-glycans at the Apical Surface of Corneal Epithelial Cells | Zendy

Mika Sumiyoshi | Zendy; Jessica Ricciuto | Zendy; Ann Tisdale | Zendy; Ilene K. Gipson | Zendy; Flavio Mantelli | Zendy; Pablo Argu ̈eso | Zendy

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Antiadhesive Character of Mucin O-glycans at the Apical Surface of Corneal Epithelial Cells

Author(s) -

Mika Sumiyoshi,

Jessica Ricciuto,

Ann Tisdale,

Ilene K. Gipson,

Flavio Mantelli,

Pablo Argu ̈eso

Publication year - 2008

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.07-1038

Subject(s) - mucin , microbiology and biotechnology , chemistry , glycan , glycosylation , adhesion , cell adhesion , cell , biology , biochemistry , glycoprotein , organic chemistry

Prolonged contact of opposite mucosal surfaces, which occurs on the ocular surface, oral cavity, reproductive tract, and gut, requires a specialized apical cell surface that prevents adhesion. The purpose of this study was to evaluate the contribution of mucin O-glycans to the antiadhesive character of human corneal-limbal epithelial (HCLE) cells.

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