Effects of Modifiers of Glycosaminoglycan Biosynthesis on Outflow Facility in Perfusion Culture | Zendy

Kate E. Keller | Zendy; John M. Bradley | Zendy; Mary J. Kelley | Zendy; Ted S. Acott | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effects of Modifiers of Glycosaminoglycan Biosynthesis on Outflow Facility in Perfusion Culture

Author(s) -

Kate E. Keller,

John M. Bradley,

Mary J. Kelley,

Ted S. Acott

Publication year - 2008

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.07-0903

Subject(s) - fibronectin , glycosaminoglycan , immunostaining , trabecular meshwork , chemistry , extracellular matrix , staining , cell culture , decorin , microbiology and biotechnology , anatomy , biophysics , biochemistry , pathology , biology , proteoglycan , immunohistochemistry , medicine , genetics , neuroscience , glaucoma

Glycosaminoglycans (GAGs) have been implicated in the regulation of outflow resistance of aqueous humor flow through the trabecular meshwork (TM). Their role was further investigated by assessment of the effects of chlorate, an inhibitor of sulfation, and beta-xyloside, which provides a competitive nucleation point for addition of disaccharide units, in anterior segment perfusion culture.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research