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Vascular Precursors in Developing Human Retina
Author(s) -
Takuya Hasegawa,
D. Scott McLeod,
Tarl W. Prow,
Carol Merges,
Rhonda Grebe,
Gerard A. Lutty
Publication year - 2008
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.07-0632
Subject(s) - retina , biology , retinal , microbiology and biotechnology , cxcr4 , inner limiting membrane , nerve fiber layer , inner nuclear layer , anatomy , receptor , pathology , neuroscience , medicine , biochemistry , chemokine
Prior investigation has demonstrated that angioblasts are present in the inner retinas of human embryos and fetuses and that they differentiate and organize to form the primordial retinal vasculature. The purpose of this study was to characterize these angioblasts further and examine ligands that might control their migration and differentiation.

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