Hyperosmolarity-Induced Cornification of Human Corneal Epithelial Cells Is Regulated by JNK MAPK | Zendy

Zhuo Chen | Zendy; Louis Tong | Zendy; Zhijie Li | Zendy; Kyung Chul Yoon | Zendy; Hong Qi | Zendy; William J. Farley | Zendy; DeQuan Li | Zendy; Stephen C. Pflugfelder | Zendy

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Hyperosmolarity-Induced Cornification of Human Corneal Epithelial Cells Is Regulated by JNK MAPK

Author(s) -

Zhuo Chen,

Louis Tong,

Zhijie Li,

Kyung Chul Yoon,

Hong Qi,

William J. Farley,

DeQuan Li,

Stephen C. Pflugfelder

Publication year - 2008

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.07-0569

Subject(s) - viability assay , apoptosis , microbiology and biotechnology , mapk/erk pathway , osmotic concentration , osmotic shock , corneal epithelium , biology , cell , downregulation and upregulation , cell culture , small interfering rna , stimulation , epithelium , transfection , signal transduction , biochemistry , endocrinology , genetics , gene

To evaluate the effects of hyperosmolar stress on expression of cornified envelope (CE) precursors and transglutaminases (TGs) by primary cultured human corneal epithelial (PCHCE) cells and the regulatory effects of JNK MAPK on this process.

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