Rodent Anterior Ischemic Optic Neuropathy (rAION) Induces Regional Retinal Ganglion Cell Apoptosis with a Unique Temporal Pattern | Zendy

Bernard J. Slater | Zendy; Zara Mehrabian | Zendy; Yan Guo | Zendy; Allan A. Hunter | Zendy; Steven L. Bernstein | Zendy

Open Access

Rodent Anterior Ischemic Optic Neuropathy (rAION) Induces Regional Retinal Ganglion Cell Apoptosis with a Unique Temporal Pattern

Author(s) -

Bernard J. Slater,

Zara Mehrabian,

Yan Guo,

Allan A. Hunter,

Steven L. Bernstein

Publication year - 2008

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.07-0504

Subject(s) - anterior ischemic optic neuropathy , optic nerve , retinal ganglion cell , biology , retina , retinal , ophthalmology , annexin a5 , apoptosis , optic neuropathy , programmed cell death , anatomy , medicine , neuroscience , genetics

Nonarteritic anterior ischemic optic neuropathy (NAION) results in optic nerve damage with retinal ganglion cell (RGC) loss. An NAION model, rodent anterior ischemic optic neuropathy (rAION), was used to determine AION-associated mechanisms of RGC death and associated regional retinal changes.

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