Glypican 4, a Membrane Binding Protein for Bactericidal/Permeability-Increasing Protein Signaling Pathways in Retinal Pigment Epithelial Cells
Author(s) -
Pedro Geraldes,
Michiko Yamagata,
Susan L. Rook,
Yukio Sassa,
Ronald C.W.,
Allen C. Clermont,
Benbo Gao,
Lloyd Paul Aiello,
Edward P. Feener,
George L. King
Publication year - 2007
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.07-0470
Subject(s) - protein kinase b , retinal , retinal pigment epithelium , biology , microbiology and biotechnology , phosphorylation , phosphatidylinositol , chemistry , biochemistry
Originally identified as a lipopolysaccharide binding protein with Gram-negative bactericidal activity in the leukocytes, bactericidal/permeability-increasing protein (BPI) has been shown to induce various effects in retinal cells in vivo and in vitro.
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