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Heritable Features of the Optic Disc: A Novel Twin Method for Determining Genetic Significance
Author(s) -
Alex W. Hewitt,
Johan P. Poulsen,
Wallace L.M. Alward,
Sonya L. Bennett,
Wido M. Budde,
Richard L. Cooper,
Jamie E. Craig,
John H. Fingert,
Paul J. Foster,
David F. GarwayHeath,
Catherine Green,
Christopher J. Hammond,
Sohan Singh Hayreh,
Jost B. Jonas,
Paul L. Kaufman,
Neil R. Miller,
William H. Morgan,
Nancy J. Newman,
Harry A. Quigley,
John R. Samples,
George L. Spaeth,
Konrad Pesudovs,
David A. Mackey
Publication year - 2007
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.06-1470
Subject(s) - zygosity , optic nerve , optic disc , twin study , weighting , optic disk , population , ophthalmology , optometry , anatomy , biology , medicine , glaucoma , evolutionary biology , heritability , genetics , environmental health , radiology
Numerous genetic diseases and environmental stimuli affect optic nerve morphology. The purpose of this study was to identify the principal heritable components of visible optic nerve head structures in a population-based sample of twins.

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