Open AccessA Protective Role for IL-6 in Staphylococcal Microbial Keratitis
Author(s) -
Emma B.H. Hume,
Nerida Cole,
Linda Garthwaite,
Shamila Khan,
Mark Willcox
Publication year - 2006
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.06-0340
Subject(s) - staphylococcus aureus , chemokine , immunology , microbiology and biotechnology , cytokine , keratitis , biology , medicine , interleukin , inflammation , bacteria , genetics
To determine whether interleukin-6 (IL-6) plays a protective role in Staphylococcus aureus keratitis in a gene knockout (gko) mouse model and to determine whether IL-6 may be used as a therapy to modulate host responses and control bacterial infection, thereby reducing scarring.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom