Lysophosphatidic Acid Promoting Corneal Epithelial Wound Healing by Transactivation of Epidermal Growth Factor Receptor
Author(s) -
KePing Xu,
Jia Yin,
FuShin X. Yu
Publication year - 2007
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.06-0203
Subject(s) - lysophosphatidic acid , heparin binding egf like growth factor , mapk/erk pathway , epidermal growth factor , wound healing , epidermal growth factor receptor , protein kinase b , cancer research , pi3k/akt/mtor pathway , growth factor receptor , phosphorylation , growth factor , microbiology and biotechnology , biology , chemistry , signal transduction , receptor , immunology , biochemistry
To identify the underlying mechanisms by which lipid mediator lysophosphatidic acid (LPA) acts as a growth factor in stimulating extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3'-kinase (PI3K) during corneal epithelial wound healing.
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