Open AccessFate of E-cadherin in Early RPE Cultures: Transient Accumulation of Truncated Peptides at Nonjunctional Sites
Author(s) -
Janice M. Burke,
Jeehee Hong
Publication year - 2006
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.06-0104
Subject(s) - microbiology and biotechnology , endoplasmic reticulum , cadherin , golgi apparatus , biology , organelle , chemistry , cell , biochemistry
E-cadherin is known to accumulate variably and slowly at junctions of cultured human RPE cells. The intent of this investigation was to determine what limits E-cadherin protein accumulation in RPE cells by analyzing cultures at early postplating intervals when junctions of the dominant cadherin (N-cadherin) are first forming.