Increased Extraocular Muscle Strength with Direct Injection of Insulin-like Growth Factor-I | Zendy

Brian C. Anderson | Zendy; Stephen P. Christiansen | Zendy; Steven Grandt | Zendy; Robert W. Grange | Zendy; Linda K. McLoon | Zendy

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Increased Extraocular Muscle Strength with Direct Injection of Insulin-like Growth Factor-I

Author(s) -

Brian C. Anderson,

Stephen P. Christiansen,

Steven Grandt,

Robert W. Grange,

Linda K. McLoon

Publication year - 2006

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.05-1416

Subject(s) - extraocular muscles , insulin like growth factor , muscle mass , superior rectus muscle , anatomy , medicine , intramuscular injection , endocrinology , chemistry , growth factor , receptor

Previous work has demonstrated the effectiveness of insulin-like growth factor (IGF)-II in increasing force generation in extraocular muscle (EOM). Studies in the literature have suggested that IGF-I would be even more effective than IGF-II. This study was performed to assess the effects on muscle mass and force generation of IGF-I injection in adult rabbit superior rectus muscle.

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