Detection of thebcl-2t(14;18) Translocation and Proto-Oncogene Expression in Primary Intraocular Lymphoma | Zendy

Dana Wallace | Zendy; Defen Shen | Zendy; George F. Reed | Zendy; Masaru Miyanaga | Zendy; Manabu Mochizuki | Zendy; H. Nida Sen | Zendy; Samuel S. Dahr | Zendy; Ronald Buggage | Zendy; Robert B. Nussenblatt | Zendy; ChiChao Chan | Zendy

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Detection of thebcl-2t(14;18) Translocation and Proto-Oncogene Expression in Primary Intraocular Lymphoma

Author(s) -

Dana Wallace,

Defen Shen,

George F. Reed,

Masaru Miyanaga,

Manabu Mochizuki,

H. Nida Sen,

Samuel S. Dahr,

Ronald Buggage,

Robert B. Nussenblatt,

ChiChao Chan

Publication year - 2006

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.05-1312

Subject(s) - chromosomal translocation , intraocular lymphoma , lymphoma , biology , gene , pathology , microdissection , microbiology and biotechnology , medicine , immunology , genetics

Primary intraocular lymphoma (PIOL) is a diffuse large B cell lymphoma that initially infiltrates the retina, vitreous, or optic nerve head, with or without central nervous system involvement. This study examined the expression of the bcl-2 t(14;18) translocation, the bcl-10 gene, and high expression of bcl-6 mRNA in PIOL cells.

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