The Effect of Resection on Satellite Cell Activity in Rabbit Extraocular Muscle | Zendy

Stephen P. Christiansen | Zendy; Linda K. McLoon | Zendy

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The Effect of Resection on Satellite Cell Activity in Rabbit Extraocular Muscle

Author(s) -

Stephen P. Christiansen,

Linda K. McLoon

Publication year - 2006

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.05-1069

Subject(s) - myod , extraocular muscles , myocyte , inferior rectus muscle , bromodeoxyuridine , anatomy , medial rectus muscle , myosin , antagonist , superior rectus muscle , biology , immunohistochemistry , myogenesis , medicine , endocrinology , receptor , microbiology and biotechnology

A common treatment for motility disorders of the extraocular muscles (EOMs) is a resection procedure in which there is surgical shortening of the muscle. This procedure results in rotation of the globe toward the resected muscle, increased resting tension across the agonist-antagonist pair, and stretching of the elastic components of the muscles. In the rabbit, due to orbital constraints and limited rotation, resection results in more significant stretch of the surgically treated muscle than the antagonist. This surgical preparation allows for the examination of the effects of surgical shortening of one rectus muscle and passive stretch of its ipsilateral antagonist.

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