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Neonatal Development of the Corneal Stroma in Wild-Type and Lumican-Null Mice
Author(s) -
Nicola Beecher,
Shukti Chakravarti,
Sarah Joyce,
Keith M. Meek,
Andrew J. Quantock
Publication year - 2005
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.05-0907
Subject(s) - lumican , stromal cell , stroma , cornea , extracellular matrix , fibril , wild type , matrix (chemical analysis) , chemistry , collagen, type i, alpha 1 , microbiology and biotechnology , anatomy , proteoglycan , biology , biophysics , pathology , mutant , ophthalmology , medicine , immunology , biochemistry , immunohistochemistry , chromatography , gene , decorin
Between days 8 and 14 of neonatal development, the corneal stroma of the mouse undergoes critical changes in tissue thickness, cell density, and light scattering. The authors investigate the stromal matrix structure in wild-type and lumican-deficient corneas in this developmental phase.

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