Mucin Characteristics of Human Corneal-Limbal Epithelial Cells that Exclude the Rose Bengal Anionic Dye | Zendy

Pablo Argu ̈eso | Zendy; Ann Tisdale | Zendy; Sandra Spurr-Michaud | Zendy; Mika Sumiyoshi | Zendy; Ilene K. Gipson | Zendy

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Mucin Characteristics of Human Corneal-Limbal Epithelial Cells that Exclude the Rose Bengal Anionic Dye

Author(s) -

Pablo Argu ̈eso,

Ann Tisdale,

Sandra Spurr-Michaud,

Mika Sumiyoshi,

Ilene K. Gipson

Publication year - 2005

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.05-0735

Subject(s) - rose bengal , mucin , staining , biology , chemistry , corneal epithelium , microbiology and biotechnology , lectin , epithelium , biochemistry , genetics

Rose bengal is an organic anionic dye used to assess damage of the ocular surface epithelium in ocular surface disease. It has been proposed that mucins have a protective role, preventing rose bengal staining of normal ocular surface epithelial cells. The current study was undertaken to evaluate rose bengal staining in a human corneal-limbal epithelial (HCLE) cell line known to produce and glycosylate membrane-associated mucins.

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