Atypical Composition and Ultrastructure of Proteoglycans in the Mouse Corneal Stroma
Author(s) -
Robert D. Young,
Debbie Tudor,
Anthony J. Hayes,
Briedgeen Kerr,
Yasutaka Hayashida,
Kohji Nishida,
Keith M. Meek,
Bruce Caterson,
Andrew J. Quantock
Publication year - 2005
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.04-1309
Subject(s) - keratan sulfate , dermatan sulfate , cornea , glycosaminoglycan , sulfation , chemistry , ultrastructure , chondroitin sulfate , stroma , western blot , chondroitin , stromal cell , immunostaining , extracellular matrix , fibril , heparan sulfate , microbiology and biotechnology , immunofluorescence , staining , biology , biochemistry , anatomy , immunohistochemistry , antibody , immunology , cancer research , neuroscience , gene , genetics
Recently, gene-targeted strains of mice with null mutations for specific proteoglycans (PGs) have been used for investigations of the functional role of these molecules. In the present study, the corneal stroma of the mouse was examined to provide some baseline PG morphologies in this species.
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