Innate Immune Response of Corneal Epithelial Cells toStaphylococcus aureusInfection: Role of Peptidoglycan in Stimulating Proinflammatory Cytokine Secretion | Zendy

Ashok Kumar | Zendy; Jing Zhang | Zendy; Fu-Shin X. Yu | Zendy

Open Access

Innate Immune Response of Corneal Epithelial Cells toStaphylococcus aureusInfection: Role of Peptidoglycan in Stimulating Proinflammatory Cytokine Secretion

Author(s) -

Ashok Kumar,

Jing Zhang,

Fu-Shin X. Yu

Publication year - 2004

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.04-0467

Subject(s) - lipoteichoic acid , peptidoglycan , proinflammatory cytokine , innate immune system , secretion , beta defensin , microbiology and biotechnology , biology , staphylococcus aureus , immune system , p38 mitogen activated protein kinases , tumor necrosis factor alpha , cytokine , mapk/erk pathway , signal transduction , immunology , inflammation , bacteria , biochemistry , cell wall , genetics

This study sought to elucidate the innate immune responses of cultured human corneal epithelial cells (HCECs) to infection by the Gram-positive bacterium Staphylococcus aureus and to determine the underlying mechanisms.

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