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Characterization of New Transcripts Enriched in the Mouse Retina and Identification of Candidate Retinal Disease Genes
Author(s) -
Julie Lord-Grig,
Nicolas Te ́treault,
Alan J. Mears,
Anand Swaroop,
Gilbert Bernier
Publication year - 2004
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.03-1350
Subject(s) - biology , candidate gene , retinal , retinitis pigmentosa , genetics , gene , retinal degeneration , retina , retinal pigment epithelium , neuroscience , biochemistry
Most retinal disease genes are preferentially expressed in photoreceptors, the light-sensitive cells involved in phototransduction. In addition, some of the genes linked to retinal diseases are essential for normal retinal development. The goal of this study was to identify new transcripts enriched in photoreceptors involved in retinal development or diseases.

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