Heme Oxygenase-1–Related Carbon Monoxide and Flavonoids in Ischemic/Reperfused Rat Retina
Author(s) -
Marta E. Szabo,
Éva Gallyas,
István Bak,
Andry Rakotovao,
François Boucher,
Joël de Leiris,
Norbert Nagy,
Edit Varga,
Árpád Tósaki
Publication year - 2004
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.03-1324
Subject(s) - heme oxygenase , flavonoid , retinal , ischemia , chemistry , endogeny , reperfusion injury , pharmacology , retina , biochemistry , heme , enzyme , antioxidant , medicine , biology , neuroscience
There is increasing evidence to show cytoprotective effects of various flavonoid-rich extracts and the tissue-protective capacity of flavonoid-rich extract of sour cherry is due to flavonoid components of seeds. Sour cherry seed flavonoids were evaluated for their contribution to postischemic recovery related to endogenous carbon monoxide (CO) production in rat retinas subjected to ischemia/reperfusion.
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