Identification of Gene Expression Changes Associated with the Progression of Retinal Degeneration in therd1Mouse | Zendy

Abigail S. Hackam | Zendy; R. Strom | Zendy; Dongmei Liu | Zendy; Jiang Qian | Zendy; Chenwei Wang | Zendy; Deborah C. Otteson | Zendy; Tushara L. Gunatilaka | Zendy; Ronald H. Farkas | Zendy; Itay Chowers | Zendy; Masaaki Kageyama | Zendy; Thierry Léveillard | Zendy; JoséAlain Sahel | Zendy; Peter A. Campochiaro | Zendy; Giovanni Parmigiani | Zendy; Donald J. Zack | Zendy

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Identification of Gene Expression Changes Associated with the Progression of Retinal Degeneration in therd1Mouse

Author(s) -

Abigail S. Hackam,

R. Strom,

Dongmei Liu,

Jiang Qian,

Chenwei Wang,

Deborah C. Otteson,

Tushara L. Gunatilaka,

Ronald H. Farkas,

Itay Chowers,

Masaaki Kageyama,

Thierry Léveillard,

JoséAlain Sahel,

Peter A. Campochiaro,

Giovanni Parmigiani,

Donald J. Zack

Publication year - 2004

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.03-1184

Subject(s) - biology , retinal degeneration , microarray analysis techniques , microarray , gene , gene expression , retina , microbiology and biotechnology , in situ hybridization , gene expression profiling , degeneration (medical) , genetics , pathology , neuroscience , medicine

One approach to gaining insight into the biological pathways contributing to rod and cone photoreceptor death is to identify patterns of gene expression changes. In the present study, a custom retinal microarray was developed to analyze the rd1 mouse, a well-characterized animal model of human retinal degeneration.

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