Experimental Dry Eye Stimulates Production of Inflammatory Cytokines and MMP-9 and Activates MAPK Signaling Pathways on the Ocular Surface | Zendy

Lihui Luo | Zendy; Dequan Li | Zendy; Amish Doshi | Zendy; William J. Farley | Zendy; Rosa M. Corrales | Zendy; Stephen C. Pflugfelder | Zendy

Open Access

Experimental Dry Eye Stimulates Production of Inflammatory Cytokines and MMP-9 and Activates MAPK Signaling Pathways on the Ocular Surface

Author(s) -

Lihui Luo,

Dequan Li,

Amish Doshi,

William J. Farley,

Rosa M. Corrales,

Stephen C. Pflugfelder

Publication year - 2004

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.03-1145

Subject(s) - mapk/erk pathway , kinase , zymography , microbiology and biotechnology , western blot , conjunctiva , p38 mitogen activated protein kinases , matrix metalloproteinase , chemistry , inflammation , biology , immunology , biochemistry , gene

To evaluate whether experimentally induced dry eye in mice activates mitogen-activated protein kinase (MAPK) signaling pathways, c-Jun N-terminal kinases (JNK), extracellular-regulated kinases (ERK), and p38 and stimulates ocular surface inflammation.

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