Estrogens Reduce the Expression of YKL-40 in the Retina: Implications for Eye and Joint Diseases | Zendy

JeanMarie Rakic | Zendy; Vincent Lambert | Zendy; Manuel Deprez | Zendy; Jean-Michel Foidart | Zendy; Carine Munaut | Zendy

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Estrogens Reduce the Expression of YKL-40 in the Retina: Implications for Eye and Joint Diseases

Author(s) -

JeanMarie Rakic,

Vincent Lambert,

Manuel Deprez,

Jean-Michel Foidart,

Carine Munaut

Publication year - 2003

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.02-0775

Subject(s) - retina , choroidal neovascularization , macular degeneration , ovariectomized rat , gene expression , biology , choroid , downregulation and upregulation , neovascularization , gene , real time polymerase chain reaction , hormone , endocrinology , medicine , ophthalmology , cancer research , angiogenesis , neuroscience , genetics

To identify modifications in the gene expression profile of the ocular posterior segment in ovariectomized (OVX) mice with and without substitutive estradiol therapy and to select differentially expressed genes that could be relevant to the natural history of human age-related macular degeneration (AMD).

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