Retinal Transplantation–Induced Recovery of Retinotectal Visual Function in a Rodent Model of Retinitis Pigmentosa | Zendy

Botir T. Sagdullaev | Zendy; Robert B. Aramant | Zendy; Magdalene J. Seiler | Zendy; Gustaw Woch | Zendy; Maureen A. McCall | Zendy

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Retinal Transplantation–Induced Recovery of Retinotectal Visual Function in a Rodent Model of Retinitis Pigmentosa

Author(s) -

Botir T. Sagdullaev,

Robert B. Aramant,

Magdalene J. Seiler,

Gustaw Woch,

Maureen A. McCall

Publication year - 2003

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.02-0615

Subject(s) - retinitis pigmentosa , retinal , retina , transplantation , superior colliculus , retinal degeneration , biology , ophthalmology , neuroscience , anatomy , medicine

To map the spatiotemporal decline in retinally driven activity in the superior colliculus (SC) of transgenic S334ter-line-3 rats that express a mutated rhodopsin, which causes photoreceptor degeneration. To determine whether transplantation of fetal retinal sheets into the subretinal space of these rats can recover visual activity in the SC.

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