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Age-Related Liquefaction of the Human Vitreous Body: LM and TEM Evaluation of the Role of Proteoglycans and Collagen
Author(s) -
Leonoor I. Los,
Roelofje J. van der Worp,
Marja J.A. van Luyn,
Johanna M. M. Hooymans
Publication year - 2003
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.02-0588
Subject(s) - fibril , extracellular matrix , liquefaction , electron microscope , fragmentation (computing) , chemistry , transmission electron microscopy , pathogenesis , matrix (chemical analysis) , collagen fibril , proteoglycan , biophysics , ultrastructure , anatomy , pathology , biology , materials science , biochemistry , medicine , nanotechnology , optics , ecology , physics , organic chemistry , chromatography
To evaluate morphologic aspects of age-related liquefaction of the human vitreous body by light and electron microscopy to provide a basis from which future studies directed at the pathogenesis of this phenomenon can be undertaken. The study focuses on changes in fibrillar collagen and proteoglycans (PGs).

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