Evaluation of Functional SiO2 Nanoparticles Toxicity by a 3D Culture Model | Zendy

Pascal PellenMussi | Zendy; Sylvie TricotDoleux | Zendy; Chrystelle Neaime | Zendy; Nicolas Nerambourg | Zendy; Francisco CabelloHurtado | Zendy; Stéphane Cordier | Zendy; Fabien Grasset | Zendy; Sylvie Jeanne | Zendy

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Evaluation of Functional SiO₂ Nanoparticles Toxicity by a 3D Culture Model

Author(s) -

Pascal PellenMussi,

Sylvie TricotDoleux,

Chrystelle Neaime,

Nicolas Nerambourg,

Francisco CabelloHurtado,

Stéphane Cordier,

Fabien Grasset,

Sylvie Jeanne

Publication year - 2017

Publication title -

journal of nanoscience and nanotechnology

Language(s) - English

Resource type - Journals

eISSN - 1533-4899

pISSN - 1533-4880

DOI - 10.1166/jnn.2018.14619

Subject(s) - nanotoxicology , cytotoxicity , materials science , toxicity , nanoparticle , cell culture , nanotechnology , biophysics , oxidative stress , viability assay , cell , in vitro , chemistry , biochemistry , organic chemistry , biology , genetics

as a kind of non-metal oxide SiO2 NPs have been extensively used in biomedicine, pharmaceuticals and other industrial manufacturing fields, such as DNA delivery, cancer therapy… Our group had developed a method based on microemulsion process to prepare SiO2 NPs incorporating photonic or magnetic nanocrystals and luminescent nanosized inorganic metal atom clusters. However, the toxicity of nanoparticles is known to be closely related to their physico-chemical characteristics and chemical composition.

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