Ginsenosides Extracted from Nanoscale Chinese White Ginseng Enhances Anticancer Effect | Zendy

Yanxia Ji | Zendy; Ziyu Rao | Zendy; J C Cui | Zendy; Haiying Bao | Zendy; Chunying Chen | Zendy; Chunying Shu | Zendy; Jian Gong | Zendy

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Ginsenosides Extracted from Nanoscale Chinese White Ginseng Enhances Anticancer Effect

Author(s) -

Yanxia Ji,

Ziyu Rao,

J C Cui,

Haiying Bao,

Chunying Chen,

Chunying Shu,

Jian Gong

Publication year - 2012

Publication title -

journal of nanoscience and nanotechnology

Language(s) - English

Resource type - Journals

eISSN - 1533-4899

pISSN - 1533-4880

DOI - 10.1166/jnn.2012.6443

Subject(s) - ginseng , bioavailability , ginsenoside , araliaceae , materials science , traditional medicine , hela , microscale chemistry , immune system , pharmacology , medicine , biochemistry , biology , cell , immunology , alternative medicine , mathematics education , mathematics , pathology

Ginsenosides, the major chemical composition of Chinese white ginseng (Panax ginseng C. A. Meyer), can inhibit tumor, enhance body immune function, prevent neurodegeneration. In this paper, for the first time we reported that the amount of ginsenosides in the equivalent extraction of the nanoscale Chinese white ginseng particles (NWGP) was 2.5 times more than that of microscale Chinese white ginseng particles (WGP). And the extractions from NWGP (1000 microg/ml) reached a high tumor inhibition of 64% exposed to human lung carcinoma cells (A549) and 74% exposed to human cervical cancer cells (Hela) after 72 h. Our work shows that the nanoscale Chinese WGP greatly improves the bioavailability of ginsenosides.

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