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What Is Allergic Bronchopulmonary Aspergillosis (ABPA)?
Author(s) -
藤井広美,
林涼子,
田口順,
荒川正博
Publication year - 2014
Publication title -
american journal of respiratory and critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.272
H-Index - 374
eISSN - 1535-4970
pISSN - 1073-449X
DOI - 10.1164/rccm.1906p3
Subject(s) - allergic bronchopulmonary aspergillosis , medicine , aspergillosis , aspergillus fumigatus , immunology , intensive care medicine , immunoglobulin e , antibody
Aspergillus is a type of fungus (also referred to as a mold), that is commonly found in the environment. It can be found in the soil, dust, water, and rotting or decaying vegetation (like dead leaves or compost piles), marijuana, and some foods and ground spices. The fungus forms into spores which are very small particles that can float in the air. Most people inhale its spores from the air, but do not have any problems from being exposed. In most cases, the fungus can live in the mucus in the breathing tubes (airways). This is called colonization. Having Aspergillus in your airways does not mean you have or will have a sudden (acute), and serious infection by this fungus. Our immune system usually helps protect the body from infections like these. In some people who have a weakened immune system, Aspergillus can get into the lungs, causing an acute infection. (For more about Aspergillus infection, see the ATS Patient Information Series fact sheet: Aspergillosis in the Fungal Disease Series). However, in a few cases, this exposure to Aspergillus triggers an allergic immune response without invading the tissues that leads to ABPA (allergic bronchopulmonary aspergillosis).

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