Fragility Index Meta-Analysis of Randomized Controlled Trials Shows Highly Robust Evidential Strength for Benefit of <3 Hour Intravenous Alteplase
Author(s) -
Katherine T Mun,
Jordan Bonomo,
David S. Liebeskind,
Jeffrey L. Saver
Publication year - 2022
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.121.038153
Subject(s) - medicine , randomized controlled trial , modified rankin scale , thrombolysis , stroke (engine) , meta analysis , fibrinolytic agent , tissue plasminogen activator , physical therapy , ischemic stroke , myocardial infarction , ischemia , mechanical engineering , engineering
Cumulative fragility index (FI) analysis enables quantification of the evidential strength of intravenous alteplase's core indication-treatment of disabling acute ischemic stroke within 3 hours of onset.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom