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Vitamin D Enhances Hematoma Clearance and Neurologic Recovery in Intracerebral Hemorrhage
Author(s) -
Jiaxin Liu,
Ning Li,
Zhiyuan Zhu,
Karrie Mei Yee Kiang,
Anson Cho Kiu Ng,
Celia M. Dong,
Gkk Leung
Publication year - 2022
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.121.037769
Subject(s) - medicine , intracerebral hemorrhage , hematoma , intracerebral hematoma , stroke (engine) , surgery , anesthesia , subarachnoid hemorrhage , mechanical engineering , engineering
Erythrophagocytosis by reparative monocyte-derived macrophage contributes to hematoma clearance and neurological recovery after intracerebral hemorrhage (ICH). Vitamin D (VitD) is a neuroprotective hormone and regulates the differentiation of monocyte-derived macrophage from monocytes. In this study, we examined the effects of VitD supplementation on monocyte-derived macrophage and hematoma clearance in rodent with ICH.

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