Effect of Occlusion Site on the Safety and Efficacy of Intravenous Alteplase Before Endovascular Thrombectomy: A Prespecified Subgroup Analysis of DIRECT-MT | Zendy

Yu Zhou | Zendy; Pengfei Xing | Zendy; Zifu Li | Zendy; Xiaoxi Zhang | Zendy; Lei Zhang | Zendy; Yongxin Zhang | Zendy; Yongwei Zhang | Zendy; Hong Bo | Zendy; Yi Xu | Zendy; Qinghai Huang | Zendy; Qiang Li | Zendy; Kaijun Zhao | Zendy; Chao Zou | Zendy; Ying Yu | Zendy; Qiao Zuo | Zendy; Shen Liu | Zendy; Liyong Zhang | Zendy; Charles B.L.M. Majoie | Zendy; Yvo B.W.E.M. Roos | Zendy; Kilian M. Treurniet | Zendy; Xiaofei Ye | Zendy; Ya Peng | Zendy; Pengfei Yang | Zendy; Jianmin Liu | Zendy

Open Access

Effect of Occlusion Site on the Safety and Efficacy of Intravenous Alteplase Before Endovascular Thrombectomy: A Prespecified Subgroup Analysis of DIRECT-MT

Author(s) -

Yu Zhou,

Pengfei Xing,

Zifu Li,

Xiaoxi Zhang,

Lei Zhang,

Yongxin Zhang,

Yongwei Zhang,

Hong Bo,

Yi Xu,

Qinghai Huang,

Qiang Li,

Kaijun Zhao,

Chao Zou,

Ying Yu,

Qiao Zuo,

Shen Liu,

Liyong Zhang,

Charles B.L.M. Majoie,

Yvo B.W.E.M. Roos,

Kilian M. Treurniet,

Xiaofei Ye,

Ya Peng,

Pengfei Yang,

Jianmin Liu

Publication year - 2021

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.121.035267

Subject(s) - medicine , modified rankin scale , odds ratio , occlusion , subgroup analysis , stroke (engine) , randomized controlled trial , randomization , surgery , confidence interval , ischemic stroke , ischemia , mechanical engineering , engineering

Recent trials showed thrombectomy alone was comparable to bridging therapy in patients with anterior circulation large vessel occlusion eligible for both intravenous alteplase and endovascular thrombectomy. We performed this study to examine whether occlusion site modifies the effect of intravenous alteplase before thrombectomy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research