Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline | Zendy

Melissa Lamar | Zendy; Sue E. Leurgans | Zendy; Alifiya Kapasi | Zendy; Lisa L. Barnes | Zendy; Patricia A. Boyle | Zendy; David A. Bennett | Zendy; Konstantinos Arfanakis | Zendy; Julie A. Schneider | Zendy

Open Access

Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline

Author(s) -

Melissa Lamar,

Sue E. Leurgans,

Alifiya Kapasi,

Lisa L. Barnes,

Patricia A. Boyle,

David A. Bennett,

Konstantinos Arfanakis,

Julie A. Schneider

Publication year - 2021

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.121.034814

Subject(s) - arteriolosclerosis , neuropathology , cerebral amyloid angiopathy , medicine , cognitive decline , dementia , disease , cognition , alzheimer's disease , cardiology , gerontology , pathology , psychiatry

Cerebrovascular disease (CVD) pathologies including vessel disease (atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and tissue injury (macroinfarcts and microinfarcts) each contribute to Alzheimer and other forms of dementia. CVD is often a complex mix of neuropathologies, with little known about the frequencies of differing combinations or their associations with cognition.

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