Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign | Zendy

Christian Ovesen | Zendy; Janus Christian Jakobsen | Zendy; Christian Gluud | Zendy; Thorsten Steiner | Zendy; Zhe Kang Law | Zendy; Katie Flaherty | Zendy; Robert A. Dineen | Zendy; Louisa Christensen | Zendy; Karsten Overgaard | Zendy; Rune Skovgaard Rasmussen | Zendy; Philip M. Bath | Zendy; Nikola Sprigg | Zendy; Hanne Christensen | Zendy

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Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign

Author(s) -

Christian Ovesen,

Janus Christian Jakobsen,

Christian Gluud,

Thorsten Steiner,

Zhe Kang Law,

Katie Flaherty,

Robert A. Dineen,

Louisa Christensen,

Karsten Overgaard,

Rune Skovgaard Rasmussen,

Philip M. Bath,

Nikola Sprigg,

Hanne Christensen

Publication year - 2021

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.120.032426

Subject(s) - medicine , intracerebral hemorrhage , tranexamic acid , placebo , interquartile range , hematoma , randomized controlled trial , anesthesia , surgery , radiology , pathology , blood loss , alternative medicine , subarachnoid hemorrhage

The computed tomography angiography or contrast-enhanced computed tomography based spot sign has been proposed as a biomarker for identifying on-going hematoma expansion in patients with acute intracerebral hemorrhage. We investigated, if spot-sign positive participants benefit more from tranexamic acid versus placebo as compared to spot-sign negative participants.

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