Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke | Zendy

Keith L. Keene | Zendy; Hyacinth I. Hyacinth | Zendy; Joshua C. Bis | Zendy; Steven J. Kittner | Zendy; Braxton D. Mitchell | Zendy; Yu-Ching Cheng | Zendy; Guillaume Paré | Zendy; Michael Chong | Zendy; Martin O’Donnell | Zendy; James F. Meschia | Zendy; WeiMin Chen | Zendy; Michèle M. Sale | Zendy; Stephen S. Rich | Zendy; Mike A. Nalls | Zendy; Alan B. Zonderman | Zendy; Michele K. Evans | Zendy; James G. Wilson | Zendy; Adolfo Correa | Zendy; Hugh S. Markus | Zendy; Matthew Traylor | Zendy; Cathryn M. Lewis | Zendy; Cara L. Carty | Zendy; Alexander P. Reiner | Zendy; Jeff Haessler | Zendy; Carl D. Langefeld | Zendy; Rebecca F. Gottesman | Zendy; Thomas H. Mosley | Zendy; Daniel Woo | Zendy; Kristine Yaffe | Zendy; YongMei Liu | Zendy; W.T. Longstreth | Zendy; Bruce M. Psaty | Zendy; Charles Kooperberg | Zendy; Leslie A. Lange | Zendy; Ralph L. Sacco | Zendy; Tatjana Rundek | Zendy; JinMoo Lee | Zendy; Carlos Cruchaga | Zendy; Karen L. Furie | Zendy; Donna K. Arnett | Zendy; Oscar Benavente | Zendy; Raji P. Grewal | Zendy; Leema Reddy Peddareddygari | Zendy; Martin Dichgans | Zendy; Rainer Malik | Zendy; Bradford B. Worrall | Zendy; Myriam Fornage | Zendy

Open Access

Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke

Author(s) -

Keith L. Keene,

Hyacinth I. Hyacinth,

Joshua C. Bis,

Steven J. Kittner,

Braxton D. Mitchell,

Yu-Ching Cheng,

Guillaume Paré,

Michael Chong,

Martin O’Donnell,

James F. Meschia,

WeiMin Chen,

Michèle M. Sale,

Stephen S. Rich,

Mike A. Nalls,

Alan B. Zonderman,

Michele K. Evans,

James G. Wilson,

Adolfo Correa,

Hugh S. Markus,

Matthew Traylor,

Cathryn M. Lewis,

Cara L. Carty,

Alexander P. Reiner,

Jeff Haessler,

Carl D. Langefeld,

Rebecca F. Gottesman,

Thomas H. Mosley,

Daniel Woo,

Kristine Yaffe,

YongMei Liu,

W.T. Longstreth,

Bruce M. Psaty,

Charles Kooperberg,

Leslie A. Lange,

Ralph L. Sacco,

Tatjana Rundek,

JinMoo Lee,

Carlos Cruchaga,

Karen L. Furie,

Donna K. Arnett,

Oscar Benavente,

Raji P. Grewal,

Leema Reddy Peddareddygari,

Martin Dichgans,

Rainer Malik,

Bradford B. Worrall,

Myriam Fornage

Publication year - 2020

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.120.029123

Subject(s) - genome wide association study , medicine , single nucleotide polymorphism , stroke (engine) , genetic association , locus (genetics) , genetics , meta analysis , population , bonferroni correction , hnf1a , disease , bioinformatics , gene , genotype , biology , environmental health , mechanical engineering , engineering , statistics , mathematics

Stroke is a complex disease with multiple genetic and environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to 3× more likely to die from stroke than European Americans.

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