Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation | Zendy

Yvonne Couch | Zendy; Naveed Akbar | Zendy; Simon Davis | Zendy; Román Fischer | Zendy; Alex M. Dickens | Zendy; Ain Neuhaus | Zendy; A I Burgess | Zendy; Peter M. Rothwell | Zendy; Alastair M. Buchan | Zendy

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Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation

Author(s) -

Yvonne Couch,

Naveed Akbar,

Simon Davis,

Román Fischer,

Alex M. Dickens,

Ain Neuhaus,

A I Burgess,

Peter M. Rothwell,

Alastair M. Buchan

Publication year - 2017

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.117.017236

Subject(s) - medicine , inflammation , proinflammatory cytokine , stroke (engine) , macrophage , extracellular vesicles , immune system , acute phase protein , monocyte , extracellular , pathological , immunology , proteomics , gene expression , pathology , microbiology and biotechnology , biochemistry , gene , in vitro , biology , mechanical engineering , engineering

Extracellular vesicles (EVs) are protein-lipid complexes released from cells, as well as actively exocytosed, as part of normal physiology, but also during pathological processes such as those occurring during a stroke. Our aim was to determine the inflammatory potential of stroke EVs.

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