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Quantitative Imaging of Cerebral Thromboemboli In Vivo
Author(s) -
DongEog Kim,
Jeong Yeon Kim,
Dawid Schellingerhout,
Ju Hee Ryu,
Su-Kyoung Lee,
SangMin Jeon,
Ji Sung Lee,
Jiwon Kim,
Hee Jeong Jang,
Jung Eung Park,
Eo Jin Kim,
Ick Chan Kwon,
Cheol-Hee Ahn,
Matthias Nahrendorf,
Kwangmeyung Kim
Publication year - 2017
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.117.016511
Subject(s) - medicine , thrombus , thrombolysis , tissue plasminogen activator , saline , fibrin , thrombosis , in vivo , nuclear medicine , myocardial infarction , microbiology and biotechnology , immunology , biology
Quantitative imaging for the noninvasive assessment of thrombolysis is needed to advance basic and clinical thrombosis-related research and tailor tissue-type plasminogen activator (tPA) treatment for stroke patients. We quantified the evolution of cerebral thromboemboli using fibrin-targeted glycol chitosan-coated gold nanoparticles and microcomputed tomography, with/without tPA therapy.

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