Impact of Glycemic Control on Efficacy of Clopidogrel in Transient Ischemic Attack or Minor Stroke Patients With CYP2C19 Genetic Variants
Author(s) -
Yi Lin,
Anxin Wang,
Jiejie Li,
Jinxi Lin,
David Wang,
Xia Meng,
Lixian Ou,
Weiqi Chen,
Xingquan Zhao,
Liping Liu,
Yilong Wang,
Yongjun Wang
Publication year - 2017
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.016463
Subject(s) - medicine , clopidogrel , aspirin , cyp2c19 , stroke (engine) , hazard ratio , antiplatelet drug , glycemic , proportional hazards model , confidence interval , cardiology , mechanical engineering , cytochrome p450 , metabolism , insulin , engineering
Dysglycemia may influence the predictive value of CYP2C19 loss-of-function allele for clinical efficacy of antiplatelet drug, but the role of glycated albumin (GA) remains unclear in patients with stroke on antiplatelet drugs.
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