Low- Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy | Zendy

Thompson Robinson | Zendy; Xia Wang | Zendy; Hisatomi Arima | Zendy; Philip M. Bath | Zendy; Laurent Billot | Zendy; Joseph P. Broderick | Zendy; Andrew M. Demchuk | Zendy; Geoffrey A. Donnan | Zendy; Jong S. Kim | Zendy; Pablo M. Lavados | Zendy; Tsong-Hai Lee | Zendy; Richard I. Lindley | Zendy; Sheila Cristina Ouriques Martins | Zendy; Verónica V. Olavarría | Zendy; Jeyaraj Pandian | Zendy; Mark Parsons | Zendy; Octávio Marques PontesNeto | Zendy; Stefano Ricci | Zendy; Shoichiro Sato | Zendy; Vijay K. Sharma | Zendy; Thang Huy Nguyen | Zendy; Ji-Guang Wang | Zendy; Mark Woodward | Zendy; John Chalmers | Zendy; Craig S. Anderson | Zendy

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Low- Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy

Author(s) -

Thompson Robinson,

Xia Wang,

Hisatomi Arima,

Philip M. Bath,

Laurent Billot,

Joseph P. Broderick,

Andrew M. Demchuk,

Geoffrey A. Donnan,

Jong S. Kim,

Pablo M. Lavados,

Tsong-Hai Lee,

Richard I. Lindley,

Sheila Cristina Ouriques Martins,

Verónica V. Olavarría,

Jeyaraj Pandian,

Mark Parsons,

Octávio Marques PontesNeto,

Stefano Ricci,

Shoichiro Sato,

Vijay K. Sharma,

Thang Huy Nguyen,

Ji-Guang Wang,

Mark Woodward,

John Chalmers,

Craig S. Anderson

Publication year - 2017

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.016274

Subject(s) - medicine , intracerebral hemorrhage , thrombolysis , modified rankin scale , odds ratio , confidence interval , stroke (engine) , clinical endpoint , fibrinolytic agent , anesthesia , randomized controlled trial , tissue plasminogen activator , ischemic stroke , subarachnoid hemorrhage , myocardial infarction , engineering , mechanical engineering , ischemia

Many patients receiving thrombolysis for acute ischemic stroke are on prior antiplatelet therapy (APT), which may increase symptomatic intracerebral hemorrhage risk. In a prespecified subgroup analysis, we report comparative effects of different doses of intravenous alteplase according to prior APT use among participants of the international multicenter ENCHANTED study (Enhanced Control of Hypertension and Thrombolysis Stroke Study).

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