White Matter Imaging Correlates of Early Cognitive Impairment Detected by the Montreal Cognitive Assessment After Transient Ischemic Attack and Minor Stroke | Zendy

Giovanna Zamboni | Zendy; Ludovica Griffanti | Zendy; Mark Jenkinson | Zendy; Sara Mazzucco | Zendy; Linxin Li | Zendy; Wilhelm Küker | Zendy; Sarah T. Pendlebury | Zendy; Peter M. Rothwell | Zendy

Open Access

White Matter Imaging Correlates of Early Cognitive Impairment Detected by the Montreal Cognitive Assessment After Transient Ischemic Attack and Minor Stroke

Author(s) -

Giovanna Zamboni,

Ludovica Griffanti,

Mark Jenkinson,

Sara Mazzucco,

Linxin Li,

Wilhelm Küker,

Sarah T. Pendlebury,

Peter M. Rothwell

Publication year - 2017

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.016044

Subject(s) - medicine , montreal cognitive assessment , stroke (engine) , cognitive impairment , hyperintensity , cognition , minor stroke , ischemic stroke , white matter , leukoaraiosis , neuroimaging , cardiology , magnetic resonance imaging , psychiatry , radiology , ischemia , stenosis , mechanical engineering , engineering

Among screening tools for cognitive impairment in large cohorts, the Montreal Cognitive Assessment (MoCA) seems to be more sensitive to early cognitive impairment than the Mini-Mental State Examination (MMSE), particularly after transient ischemic attack or minor stroke. We reasoned that if MoCA-detected early cognitive impairment is pathologically significant, then it should be specifically associated with the presence of white matter hyperintensities (WMHs) and reduced fractional anisotropy (FA) on magnetic resonance imaging.

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